| Sanity of Morris | StickyLock | 2/10 | |
| Scarface: The World is Yours | Vivendi | 8/10 | |
| Scram Kitty and His Buddy on Rails | Dakko Dakko | 9/10 | |
| Secret Files 2: Puritas Cordis | Deep Silver | 8/10 | |
| SEGA Bass Fishing | SEGA | 6/10 | |
| SEGA Superstars Tennis | SEGA | 8/10 | |
| Semispheres | Vivid Helix | 8/10 | |
| Shantae: Risky's Revenge | WayForward | 8/10 | |
| Shantae: Risky's Revenge - Director's Cut | WayForward | 7/10 | |
| Shantae: Risky's Revenge - Director's Cut | WayForward | 6/10 | |
| Shantae: Risky's Revenge - Director’s Cut | WayForward | 7/10 | |
| Sherlock Holmes: Crimes & Punishments | Focus Home | 7/10 | |
| Sherlock Holmes: Crimes & Punishments | Focus Home | 7/10 | |
| Shin Megami Tensei: Strange Journey Redux | Atlus | 10/10 | |
| Sid Meier's Civilization VI: Rise and Fall | 2K | 9/10 | |
| Sight Training | Nintendo | 8/10 | |
| SIGNALIS | Humble | 9/10 | |
| Sin and Punishment 2: Successor of the Skies | Nintendo | 10/10 | |
| Sin and Punishment: Successor of the Earth | Nintendo | 8/10 | |
| Sisters Royale | Alfa System | 7/10 | |
| Sisters Royale (Second Opinion) | Alfa System | 7/10 | |
| Small Radios Big Televisions | Adult Swim | 7/10 | |
| Smoots World Cup Tennis | JanduSoft | 3/10 | |
| Sonic Boom: Rise of Lyric | Annapurna | 1/10 | |
| Sonic the Hedgehog 4 - Episode I | SEGA | 7/10 | |
| Star Wars Episode I: Racer | Aspyr | 7/10 | |
| Star Wars Episode III: Revenge of the Sith | LucasArts | 7/10 | |
| Stasis: Bone Totem | Feardemic | 7/10 | |
| SteamWorld Heist | Image & Form | 9/10 | |
| SteamWorld Heist | Image & Form | 8/10 | |
| SteamWorld Heist | Image & Form | 9/10 | |
| SteamWorld Heist | Image & Form | 7/10 | |
| SteamWorld Heist II | Thunderful | 9/10 | |
| SteamWorld Heist: Ultimate Edition | Image & Form | 9/10 | |
| Steel & Steam: Episode 1 | Digerati Distribution | 6/10 | |
| Stellaris | Paradox | 9/10 | |
| Stellaris: Apocalypse | Paradox | 5/10 | |
| Stellaris: Distant Stars | Paradox | 7/10 | |
| Stellaris: Federations | Paradox | 6/10 | |
| Stellaris: Humanoids | Paradox | 4/10 | |
| Stellaris: Leviathans | Paradox | 6/10 | |
| Stellaris: Necroids | Paradox | 3/10 | |
| Stellaris: Synthetic Dawn | Paradox | 5/10 | |
| Stellaris: Utopia | Paradox | 6/10 | |
| Stranded Sails - Explorers of the Cursed Islands | Merge Games | 3/10 | |
| Strange Brigade | Rebellion | 8/10 | |
| Strangeland | Wadjet Eye | 8/10 | |
| Stranger of Paradise: Final Fantasy Origin | Square Enix | 7/10 | |
| Stranger of Sword City | NIS America | 8/10 | |
| Stranger of Sword City | NIS America | 4/10 | |
| Stranger of Sword City Revisited | NIS America | 8/10 | |
| Suikoden Tierkreis | Konami | 9/10 | |
| Super Mario Advance 3: Yoshi's Island | Nintendo | 9/10 | |
| Super Mario World 2: Yoshi's Island | Nintendo | 9/10 | |
| Super Robot Taisen OG Saga: Endless Frontier | Atlus | 7/10 | |
| Super Robot Taisen: Original Generation | Atlus | 9/10 | |
| Super Tennis | Abyssal Arts | 9/10 | |
| Super Tennis Blast | Unfinished Pixel | 6/10 | |
| Supreme League of Patriots Issue 1 - A Patriot is Born | Phoenix Online Publishing | 4/10 | |
| Supreme League of Patriots Issue 2 - Patriot Frames | Phoenix Online Publishing | 7/10 | |
| Supreme League of Patriots Issue 3 - Ice Cold in Ellis | Phoenix Online Publishing | 5/10 | |
| Swap This! | Two Tribes | 6/10 | |
| Sword Art Online: Alicization Lycoris | Bandai Namco | 6/10 | |
| Sympathy Kiss | Reef Entertainment | 8/10 | |